Glass Ampoule Filling Machine

Glass Ampoule Filling Machine

Description:

A Glass Ampoule Filling Machine is a specialized pharmaceutical packaging machine designed to fill liquid medicines, vaccines, or chemical solutions into glass ampoules with high accuracy, hygiene, and speed. Ampoules are sealed glass containers that ensure a sterile, single-use dose — ideal for injectable drugs, laboratory chemicals, and clinical diagnostics.

These machines automate the process of filling, sealing, and sometimes pre-washing or pre-sterilizing ampoules, making them critical to the pharmaceutical and biotech industries.

How It’s Made:

Glass ampoule filling machines are precision-engineered with cleanroom-compatible materials, ensuring contamination-free operation.

Manufacturing Steps:

Structure Fabrication:
Stainless steel frames (SS 304/316) are fabricated to house all mechanical and pneumatic/electrical parts.
Drive Mechanism Installation:
High-precision servo or cam-driven systems are installed to ensure synchronized ampoule movement.
Filling System Assembly:
Peristaltic pumps, piston pumps, or syringe filling systems are mounted based on required volume accuracy.
Ampoule Holders & Grippers:
Specially machined holders or racks are installed to securely transport the ampoules during filling and sealing.
Sealing Unit Integration:
Gas flame torch (oxy-LPG or oxy-hydrogen) units are installed to hermetically seal the ampoules after filling.
Control Panel & Sensors:
A PLC-based control system with touchscreen HMI is integrated for real-time process monitoring, speed, and fill-volume control.
Sterilization Compliance:
Entire structure is built to GMP and cleanroom standards for contamination-free operation.

Where It’s Used:

Pharmaceutical manufacturing (injectables, vaccines)
Biotechnology labs
Veterinary medicine units
Clinical research centers
Cosmetic and fragrance industry (for sample vials)
Chemical & diagnostic reagent production

Key Features:

Filling Capacity: 1 ml to 30 ml (customizable)
Output Speed: 30 – 150 ampoules/min (depending on model)
Sealing System: LPG + Oxygen flame-based or Electric arc
Control: PLC with HMI interface
Construction: SS 316 contact parts for hygiene
Change Parts: Interchangeable format parts for different ampoule sizes
Nitrogen Flushing Option: Available before and after filling
Vacuum Leak Detection System: Optional
Integrated Ampoule Washing & Drying Unit: Optional in combo lines

Importance in Pharma & Healthcare:

Ensures sterile packaging, which is critical for injectables
Supports mass production of life-saving medicines and vaccines
Meets WHO, GMP, and FDA standards for safety
Protects drugs from air, moisture, and contamination
Enables accurate dosing and reduces human error

Advantages:

Sterile and Contamination-Free Filling
Ensures aseptic processing in cleanroom environments.
High Precision & Accuracy
Fills exact dosage in each ampoule using servo or syringe-based systems.
Fast & Scalable
Ideal for both small-batch and high-volume production lines.
Reduced Wastage
Auto-reject systems remove underfilled or misaligned ampoules.
Compact Footprint
Modern machines are designed to save floor space in pharma units.
Easy to Operate
User-friendly touchscreens, recipe saving, and alarm systems.
Safe Sealing
Flame sealing ensures hermetic sealing without cracking.

Why Choose a Glass Ampoule Filling Machine in India?

Indian manufacturers offer cost-effective, export-quality machines
Machines are designed with global GMP standards in mind
Available with customization for niche pharmaceutical needs
Local service, spare availability, and training support
Trusted by Indian pharma giants and international clients alike